Theobald Smith Award in Medical Sciences, American Association for the Advancement of Scienc
Commonwealth Fund Fellow, Institut Pasteur
Harvey Lecturer
Jacobeaus Lecturer, Stockholm Sweden

Research Interests

A major part of Dr. London's research has been concerned with the biosynthesis of hemoglobin and its regulation at the level of translation of messenger RNA and at the level of transcription of the globin genes.

Reference Publications

Imren S, Payen E, Westerman KA, Pawliuk R, Fabry ME, Eaves CJ, Cavilla B, Wadsworth LD, Beuzard Y, Bouhassira EE, Russell R, London IM, Nagel RL, Leboulch P, Humphries RK. Permanent and panerythroid correction of murine beta thalassemia by multiple lentiviral integration in hematopoietic stem cells. Proc Natl Acad Sci USA. 2002 Oct 29;99(22):14380-5.
Pawliuk R, Westerman KA, Fabry ME, Payen E, Tighe R, Bouhassira EE, Acharya SA, Ellis J, London IM, Eaves CJ, Humphries RK, Beuzard Y, Nagel RL, Leboulch P. Correction of sickle cell disease in transgenic mouse models by gene therapy. Science. 2001 Dec 14;294(5550):2368-71.
Crosby JS, Chefalo PJ, Yeh I, Ying S, London IM, Leboulch P, Chen JJ. Regulation of hemoglobin synthesis and proliferation of differentiating erythroid cells by heme-regulated eIF-2alpha kinase. Blood. 2000 Nov 1;96(9):3241-8.

Courses Taught

HST 140 - FA 2013 - Molecular Medicine

Molecular Medicine

People

Faculty

imlondon@mit.edu

Courses Taught