Associate Professor of Otology and Laryngology, Harvard Medical School, Massachusetts Eye and Ear Infirmary
PhD in EECS, MIT 1993
SM in EECS, MIT 1986
SB in EECS, MIT 1983
American Association for the Advancement of Science
Association for Research in Otolaryngology
Society for Neuroscience
Dr. Melcher seeks to understand how sound is coded in population neural activity of the human central auditory system. Her work uses functional MRI to assay brain activity and high-resolution structural MRI to examine brain architecture. Dr. Melcher's current research falls into three broad categories: (1) determining functional and structural organizational principles of the human central auditory system, (2) identifying neural correlates of sound perception, and (3) establishing the neural mechanisms of tinnitus, a poorly understood auditory disorder with no uniformly effective treatment.
Harms, M.P., Guinan, Jr. J.J., Siglovsky, I.S., Melcher, J.R. Short-term sound temporal envelope characteristics determine multisecond time-patterns of activity in human auditory cortex as shown by fMRI. J. Neurophysiol. 2005; 93: 210-222.
Penagos, H., Melcher, J.R., Oxenham, A.J. A neural representation of pitch salience in nonprimary human auditory cortex revealed with functional magnetic resonance imaging. J. Neurosci. 2004; 24: 6810-6815.
Melcher JR, Sigalovsky IS, Guinan JJ,Jr., Levine RA. Lateralized tinnitus studied with functional magnetic resonance imaging: abnormal inferior colliculus activation. J. Neurophysiol. 2000; 83: 1058 - 1072.